“Open With” containing duplicate apps
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Today I noticed that when I right-clicked on an image and selected “Open With” from the contextual menu - it took a while (a few seconds to open) and that it contained duplicated entries of several of my applications.
It seems that it is a known issue - and the fix is pretty straight forward.
Open up your Terminal and enter the following code:
cd /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/LaunchServices.framework/Versions/A/Support/ ./lsregister -kill -domain local -domain system -domain user
Once the above has been executed (can take a bit, just wait for the prompt to show up again) then exit your Terminal and log out of your Mac and log back in and then it should be resolved.
The problem in my case seems to be caused by the fact that I had a mounted disk with a clone of my main disk on - so all “open with” applications where duplicated as they existed two places. I have solved the problem by not keeping the clone mounted - and simply leave the mounting to SuperDuper that I use for my cloning (after the backup SuperDuper automatically un-mount the disk).

January 29th, 2007 at 22:36
i’m having the same problem. is your external drive partitioned? mine is split into two partitions so i can’t unmount just the “bootable” backup without unmounting the other partition as well. do you think running the same code would work for me?
January 30th, 2007 at 3:51
Yes my drive is partitioned as well. What I do is to unmount the bootable partition drive (which also unmount the other partition) and then I manually mount the second partition (the bootable is not mounting in that case) - and yes the code in this post works in that case.
Not elegant, I know, but it does work.